Savage99...I'm guessing from your post you like Weatherby rifles and cartridges...? A little tongue and cheek...!
Hairsmoker...I compared the 264WM and against the 270WCF and there are several bullets in the middle weights with similar BC's and the speeds are only 50-75fps one way or the other. Then I got interested in the Weatherby calibers for the first time in my life and WHOW what a difference. Those sorts of velocity differences are significant and seriously reduce the wind and gravity factors on longer shots and bigger deer. I already have three 257 Roberts, two 270WCF's, a 358WCF, a 350RM and a 338WM for hunting deer and elk around timbered land with clear cuts and farmed fields in Idaho. This rifle will be for the plains and prairies of Colorado, Kansas, NM etc.
A factory, semi custom rifle ( Remington or more so on the Weatherby ) seems like a good deal.
I also looked at the 7mm Remington magnum, but looks like the 270WM has it beat by a good amount also using deer weight bullets.
I am FORTUNATE and have several choices of rifle/caliber each time I hunt and only hunt once a year and range shoot two additional times a year, so expensive ammo and barrel life should not be a problem or great expense. I reload also.
I look at 40-60 rounds of expensive Weatherby ammunition as 30-40 deer over the rest of my hunting life. In many years of hunting I've never forgotten my ammo, but have forgotten my watch once which messed up the " meet back here in four hours " plan...LOL