In rifles of equal weight, both firing 270gr bullets, the 375 Ruger is ~150fps faster than the 375H&H, for a whopping 5lbs difference, in recoil; about 13% more. It's hard to imagine that is going to be a real decision-maker, if you're in the market for such a powerful rifle. Like so many other "this, or that" discussions, there are probably several other factors that will be of more importance than the actual cartridge being chosen.
Also, I'm sure if you need a couple of boxes of ammo while you're in Africa, you'll be able to find it, with enough cash waving around.
Also, I'm sure if you need a couple of boxes of ammo while you're in Africa, you'll be able to find it, with enough cash waving around.