Much depends upon the bullet and the hardness of the bullet, as that will dictate pressures developed, to a degree, with softer bullets spiking pressures more quickly than harder ones. Also note that most of these guns, while having a .357"-.376" groove diameter, have huge throats in them, and usually a .377" diameter bullet shoots best in them.
The loads listed below use Beartooth's BHN 21 GC bullets.
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