I shoot the Hornady 300 gr. Jacketed, but I will forewarn that they are explosive. I shot my deer at about 2200fps and it took out 4 ribs and 5 vertebrae. I am going to work up some loads using the 350 fp and round nose version interlocks next. I did however love the accuracy as I was getting .875" to 1.25" groups at 100 yards with iron sights. It'd probably be a killer bullet doing silhouette competitions or similar. 8) My load for them with the best accuracy was 46.7gr. Reloader7, which is the only powder I use in the .45-70 platform now. I also loaded 325 gr. FTX bullets with a very minor variation in elevation of POI. These also shot very accurately. At speeds over about 1800fps, they are pretty explosive also. I load FTX's up with 34.3 gr. Reloader7 for trap door level loads and my wife's loads as she's pretty recoil sensitive. Try them out, but I wouldn't use these for large, ie. elk, moose etc game.
I do use Unique for my round ball loads though.