Me personally I love steel framed pistols and grew up shooting my PawPaws 1911 and his 357 Mag. I have had many 1911's over the years and carried a full size 45acp until last year when my buddy convinced me to try out his Beretta 92fs and I now have a 92X RDO as as my CCW...But I love the 45acp and have cast tons of them I go with the middle of the road approach with target ammo and use 200 grain swc's to practice with, but for carry purposes and to stop threats I have always went with good ol +P Hydra-Shoks because 235 grains has been proven over time and they're my personal favorite. I think it really depends on the threats response to the trauma that occurs when taking a bullet to determine how quickly they'll go down. For the purposes of creating the wound cavity. I'm on the side of the heavier they are the more lead to expand out further than the lighter ones. If I'm going to shoot lower than 200 grains to get more speed or less recoil I'll just shoot a 9mm. Plus if you go with subsonic seismic rounds you can shoot 185 grain 9mm bullets.
Second place is the first loser