For one yr the 454Casull was chambered in a Win/Browning Hi-Wall action. Not much info was ever posted on results. The 454 is such a specialized, exotic cartridge that the handgun crowd wants to keep it a handgun round IMO. From my experience with the 45-70 gov't reloading, I would think that the 454 will approach that performance level at higher pressures.Revolvers can achieve 1800fps with .001" cylinder gaps and pressures in the 60,000psi range.