I've read reports, by the late Skeeter Skelton, among others, IIRC, of lead bullet loads producing higher pressures in revolvers than same-weight same-charge jacketed bullet loads as the charge approaches upper limits. The theory was that the bullet base gets upset enough by pressure to fill laterally into the forcing cone, making it tougher to force into the bore. I don't know if that has been validated or not?
Certainly, if you drive them too hard you get a lot of lead spray onto the underside of the top strap of the revolver frame from gas cutting. Accuracy isn't so great if they are pushed too hard. Elmer Keith developed the .44 Mag using cast bullets, so that much pressure isn't too much. I'm not sure where, exactly, you cross the line?
I've also not heard of that phenomenon mentioned for jacketed bullets before? Even if possible, common sense suggests a bullet designed to expand at .45 ACP velocities will be going too fast to hold together well on impact out of a .454, so then the question becomes, what's the point of trying? The 250 grain XTP is not one of those .45 ACP bullets, however. It is used in the Savage 10ML with sabots, among other things, from which they leave the muzzle at nearly 2200 fps and are still sturdy enough for hunting deer.