If you're looking for a load in the 750 to 800 fps area, try Trailboss powder. 6gr.under a 255gr. RNFP in my 4in. Redhawk over MY chrony, 12 rounds, 749 to 760, right at 800fps in 5 1/2in BBH. Light recoil, VERY accurate and clean burning. Smells a little funny though. Fills the 45 case nicely so no worry about a double charge. Meters well through my powder measures. I've used alot of different powders in the 45 colt (rugers) including Unique, HS6, (11.0gr. is good in my guns) W231, 2400, bullseye, Blue Dot, W296 &H110, (still use those two for heavy loads (infrequent) and 7 and 800X. I've just about convinced myself that the 6gr. trailboss load will be my everyday load for hiking and Horseback in my area as we're fresh out of Grizzleys and Rhinos in Southern Washington State...

It's easy to load, easy to shoot, and will bring about the demise of anything I will need to shoot around here. I like it..