The only caution that goes with it is the possibility of creating so-called "secondary pressure spikes" with slow powders and light bullets. I've concluded these are not true pressure spikes, but happen when a mass of accelerating gas slams into the base of a bullet that has slowed after initial acceleration. That happens because a slow burning powder hasn't been able to make gas fast enough to keep up with the expansion of volume behind the fast moving light bullet. Thus, pressure drops and the bullet is then slowed by friction. That collision, when the gas catches up, upsets the bullet diameter. The radial impact hammering effect swells the steel. That swell spreads out the length of the steel, and back near the breech it produces strain same as would be produced if actual pressure were stretching it radially.
The risk isn't in pressure rise, therefore, but occasionally that the bullet upset can actually bulge or even crack the barrel at the bullet location. Texas gunsmith Charlie Sisk has been able to break the muzzles off .338 barrels this way on demand. It doesn't seem to happen in barrels shorter than 18" or 20", as the bullets don't usually have time to slow down enough and/or the gas to catch up enough in those and shorter tubes. But you can see strain gauge pressure curves showing the apparent pressure spike by scrolling down to the last trace and second from last trace,
here, even though its really just a reflection of that momentary stretch up nearer the muzzle, and overlayed on the actual reading of pressure-induced strain as it travels rearward in th barrel.
The fired cases from these readings don't show pressure signs, which is one way you know it isn't caused by true pressure back at the chamber. The stress on the barrel at the actual event, though, is great enough to discourage me from running slow powder with light bullets.
