MikeG care to share?Load info.
A heapin' helpin' of H110
Actually, it was WW296, but that sounded better. Anyway... you do have to work up loads, and I've since switched to surplus WC820, but many of the reloading manuals have "Ruger Only" loads in the 30,000 CUP range for the full sized Blackhawks, Bisleys, and old (no longer in production) Vaqueros. You DON'T want to do such things in the current small-frame Vaquero....
Hodgdon, Speer, etc...... the data is out there. Should run 1200 - 1300fps at the muzzle depending on the gun and barrel length with 300 grain bullets. There are also specialty ammo makers such as Buffalo Bore and Garrett (?) and Cor-Bon that have similar offerings.
If you get a Bisley then there's no worries and they handle the recoil better, my opinion. Anyway, I used a stainless 5.5" Bisley on the buff, and it's a combination I can recommend.
They'll also go through a pig, lengthwise, and that takes the steam out of them, quick!