Nosler bullets, if you pinch them sideways in a caliper just above the pressure ring at the corner of the bearing surface and BT or heel, depending on whether it is BT or FB, and look at the crack of light coming through, all have a slight taper. It's probably just to make it easier to eject them from the forming die, but some guns hate that taper and some love it above and beyond anything else.
I agree with the suggestions to try the flat base 53 grain Sierra MatchKing bullet. Flat bases in general require less care and effort to get shooting accurately. These work well with a number of powders.
Bryan Litz says Hornady soft points tend to slump in the barrel more than others, spoiling their ballistic coefficient. He says the Sierra softpoints slump least. Nonetheless, with an ancient box of Hornady soft points, my .222 Rem will drill 1/4-3/8" cloverleaves all day long. So you're not yet at the 100 yard potential for these bullets at over an moa.
I saw something written by a fellow who co-purchased a Manson crowning tool and ultimately got to recrown almost all the rifles for his club's members. Fully 50% shot better afterward. I mention this just to point out the best load in the world won't shoot if the platform isn't right. You should check your crown carefully and bedding and other accuracy factors if you get stuck for load workup steps. I also recommend you look through
Dan Newberry's method of finding a best load. You may choose some personal variations later, but it's a good starting point. The round robin can also be applied to finding a best seating depth before using it to find the best powder charge.