I have reloaded mass quantities of 5.56mm/.223 on a Dillon XL650. I use Hornady spray case lube, according to the directions on the can. My press has an automatic case feeder, and I have a seperate toolhead, measure, etc. for quick setup.
Having said all that, I am switching back to a single stage press for this caliber, for the following reasons:
1. Reloading on a progressive, unless you do it in a couple of steps (size them all, then trim them all, then load them all), does not allow you to trim brass, and that can become important after a couple of firings, especially if you are picking up range brass of unknown origin.
2. I have had a couple experiences of failure to fully resize the cases because of an improperly adjusted sizing die. I don't know if it crept up a fraction of a turn or if it was a mistake I made when setting it up, but I wound up with several hundred rounds that would work OK in a Mini-14 but jammed occasionally in an AR.
3. I have had some rounds with bad crimps for the same reason as above.
Because of the extreme danger if an oversize or too long round is almost, but not quite, chambered, and the possibility of an out-of-battery detonation, I have decided I would rather sacrifice speed for the increased safety of seeing every round properly loaded.
Now, there will be many who think I'm getting carried away here, and I have never had any kind of accident with several thousand rounds loaded, but I guess I am getting old enough to have the patience to do this more deliberately.
I will still be using the 650 to crank out oodles of pistol ammo.