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They'll work just fine if you keep the shots in the boiler room and away from the front shoulder. If the bullet hits a rib you will have a ping-pong ball sized entrance hole and one dead deer.I loaded up some 130 Grain BT's in my 270 Weatherby Magnum, 3 shots under a nickle, however I am scared to use them on Whitetails. They are flying a little under 3300 feet per second. I loaded up some 140 Grain Accubonds for deer season. They are having similar performance at the range.
I used them in my .270win at 3100fps and at 75yds the results were phenomenal and quite terminal. At 175yds the buck just sat down on his butt and fell over.