Yes. There are outfits that sell slugs with sabots and slug molds and sabots independently. The outfits that sell supplies have tools for forming roll crimps over slug sabots that chuck in a drill press or something similar. SlugsRus.com has the tools plus a limited selection of saboted slugs, for example. There's another outfit with more, but I've forgotten the name.
Simply substituting an ML sabot for a slug sabot probably won't work out both due to lack of a bore diameter match and because sabots for shotguns have a wad system built in with some give space under the slug that affect pressure. You can get molds from Lyman and Lee that allow the use of a conventional plastic shotgun wad as the sabot and allow use of a conventional star crimp.