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I've killed lots of squirrels and rabbits with stock .22LR, .22mag, .38spl and .45acp. All my deer have fallen to stock S&W M19, M686 .357s, .41mag Ruger BH, and a .44mag Ruger SBH. Deer are easy to drop; all you have to do is make a good shot. All mine were dropped with one (1) shot each.
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