" With all due respect though, I'm not impressed by 2.5" to 3" groups at 100 yards unless you're shooting open sights on that Marlin. "
I think that pretty good shooting for almost any day with an untuned factory lever action, recievcer sight (I assume) or low power scope. It is pretty hard to do everything the same, five times in a row with a pretty heavy load. 1380 fps with a 322 grain bullet is a pretty good load for a light leveraction. Managing recoil, using the same sight setting, handling recoil (follow through) are all pretty tough and those heavy -for the caliber bullets will have you talking too yourself!
If you reduce the velocity to the 1000 fps level of even slower you can really tighten up the groups.
"Typically, my goal for a lever action rifle with a receiver sight and fine post or crosshair is in the 1-1.5 MOA range for three to five rounds. "
That is a pretty tough goal for cast bullets and any lever action rifle. .44 caliber an up at low velocity you will shoot a few groups like that. Believe it or not you may come cloeser to your goal with a good paper patch bullet.
"Anyway, please describe any casting pitfalls you have run into with 457122 and how you solved them."
I personaly have had no pit falls with the 457122 mold. I have been casting hollow points with Lyman molds since I was a teen ager and I had a few problems early on. I run the melt Hot! I dip the pin into the melt initialy to get it vey hot. I often dip the sprue plate into the melt to get it hot. As long as the mold and pin start off hot and your melt is hot your only problem is paitience.